Bile And Bile Salts. Bile salts are synthesized in the hepatocytes from cholesterol. Bile salts and bile acids are polar cholesterol derivatives, and represent the major route for the elimination of the steroid from the body.
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Bile salts and bile acids are polar cholesterol derivatives, and represent the major route for the elimination of the steroid from the body. Despite the increased water solubility of bile salts, they are amphipathic molecules overall [8]. Bile salts are efficiently reabsorbed from the intestinal lumen to undergo enterohepatic circulation.
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Bile can help the body absorb those broken down products of fat within the gut. Only two of these are primary or synthesized in the liver. Unfortunately, over a third of all people who have their gallbladder taken out never fix the symptoms of gallbladder disease. Bile salts are 24 carbon water soluble products of cholesterol metabolism.