Sickling Test Pdf. Sickling had a cohen’s kappa of 0.6, solubility 0.3 and peripheral film 0.4. A sickling test is more or less a first response test to determine whether a person has the hbs (haemoglobin s) genotype or not.
(PDF) Quality Indicator Development for Positive Screen
Two methodologies form the basis for tests to screen for hemoglobin s: This test shows the presence of sickle haemoglobin. Fresh blood in any anticoagulant.
(PDF) Quality Indicator Development for Positive Screen
One drop of blood is mixed with one drop of sodium metabisulfate reagent on a slide. In case of sickle cell homozygous, solubility test was found to be fairly effective with 75.0 % and 80.85% sensitivity and specificity respectively, with the predictive value of positive test 57. The hbs genotype has a weak cell structure which gives it the tendency to fold up or cave in (sickle) when it loses oxygen. Sickle cell disease is also referred to as the inherited red blood corpuscles.